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<"Run" is a post-Britpop power ballad, composed using common time in the key of C major, with a tempo of 72 beats per minute. It is written in the common verse–chorus form, and its chord progression goes Am–Fmaj7/A–Gsus4, it repeats once, and later it changes to Am–F6/C–Gsus4, which also repeats one time, and then the sequence restarts. Lightbody's vocal range performs from A3 to F5, and the song features bass guitar, cello, drums, guitars, viola and violins as its musical instruments. Adrienne Day wrote for Spin that "Run" includes "guitar riffs”, whilst Joe Bosso described the song as "dark and moody".
A reviewer for Contactmusic.com commented about "Run". In its introduction includes a "trembling guitar", Lightbody's vocals as "velvet soft", and its refrain as "stirring stuff". Irish writer Peter Murphy called it a "strange hybrid", explaining it is "a lighter-waving anthem drenched in private grieving". Kevin Forest Moreau considered "Run" to has "plaintive lyrics, rigorous strumming, sweeping strings and a hook that yanks without reservation for the heartstrings of adolescent girls everywhere.” Claire Simpson described it as an "angst-ridden guitar ballad".>
